Jeanette Tomasino, PhD, Northwell Health Fertility, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, Ruth Bunker Lathi, MD, Stanford Fertility and Reproductive Medicine Center, Sunnyvale, CA and Alleigh L.H. Boyd, MS, Stanford University, Palo Alto, CA
Lifestyle and Genetics: High and Low Tech Approaches to Recurrent Pregnancy Loss
The first few minutes of the course will review RPL and established causes. The presenters will then review potential lifestyle causes for the disorder, proceed to treatments that have shown efficacy, and finally challenges to overcome with this approach. The final portion of the course will review chromosomal testing, its shortcomings, including incorrect diagnosis, and finally review the literature for promise in improving outcomes. At the conclusion, the presenters will provide specific, evidence-based take-aways for practitioners and describe future directions and pending research.
Kutluk H. Oktay, MD, PhD, Yale University School of Medicine, New Haven, CT, Amanda Nicole Kallen, MD, Yale University School of Medicine, New Haven, CT and Samir Babayev, MD, Mayo Clinic, Rochester, MN
Howard and Georgeanna Jones Endowed Symposium on Assisted Reproductive Technology: Mechanisms of Ovarian Follicle Development: Scientific Basis of Performing Sound Ovarian Stimulation
Ovarian stimulation and ovulation induction are the most performed treatment by reproductive endocrinology and infertility specialists. Yet most practitioners may not be up to date on the mechanisms of ovarian follicle development and foundation for ovarian stimulation. This symposium will enhance the ability of practitioners to conduct ovarian stimulation more efficiently and avoid unnecessary interventions in patient care.
Audrey J. Gaskins, ScD, Emory University, Rollins School of Public Health, Atlanta, GA, Jorge E. Chavarro, MD, ScD, Harvard School of Public Health, Boston, MA and Anne Z. Steiner, MD, MPH, Duke University, Durham, NC,
Antioxidants and Male Fertility: Should Men Take Supplements or Not?
This interactive session will take the format of a debate where one speaker will be presenting the evidence from the Cochrane review–which concluded that there was low-quality evidence from seven small randomized controlled trials suggesting that antioxidant supplementation in sub-fertile males may improve live birth rates for couples attending fertility clinics–as well as observational studies which support antioxidant supplementation. The other speaker will be focusing on the newest evidence from the MOXI trial, a large recently completed RCT of sub-fertile men taking vitamins C, D3 and E, folic acid, zinc, selenium and L-carnitine vs. placebo–in which preliminary results concluded that there was no difference in semen quality parameters or conception rates during the three months of follow-up. And, why the association between antioxidants and semen quality is likely null. Participants should walk away from the session with increased knowledge on the topic and a better understanding of how to judge and evaluate studies, particularly randomized control trials (RCT), in terms of their risk for bias and how to weigh heterogeneous evidence.